Giant checkered rabbits are adults at 4 months. It is not advisable to mate immediately at this time, as it is easy to cause premature birth and dystocia of female rabbits. Therefore, it is recommended to breed after 6 months of age. There is no fixed estrus time for giant checkered rabbits, and they can be bred and reproduced all year round, but attention should be paid to avoiding high temperature and low temperature seasons to ensure the survival of the cubs.

The pregnancy period of giant checkered rabbits is generally one moon. The delivery time of the giant checkered rabbit is usually in the middle of the night or in the early morning, and the delivery will be completed in about ten to thirty minutes. The female rabbit who has just given birth can be pregnant, but it is best to avoid this situation, because it will hurt the female rabbit very much. Physically, it is best not to let the female rabbit become pregnant more than twice in a year.

The giant checkered rabbit is different from the general rabbit species. It is not unusual to be active and playful, and like to show off very much, like to attract the attention of others, just like a natural star, every gesture is full of special atmosphere.