I don't know if you still remember a warm Japanese movie Goodbye, Kelu? I cry every time I watch it, especially when the dog is gradually moving towards life. At the end of the chapter, it was even more snot and tears holding the facial tissue box in grief. Because of this touching guide dog movie, it has led to a whirlwind of raising Labrador dogs, and also made more people pay attention to the great task given to guide dogs, and the government, shops, and public facilities are also more humane. Provide a living space for guide dogs and blind people.

Although occasionally it happens that the store prohibits guide dogs from entering, but the movie has a profound impact on the audience, and everyone will help come forward Uphold justice and report store owners, greatly improving the quality of life of guide dogs and blind people. However, when everyone is raising Labrador dogs, have they done their homework? The more inbred animals are, the easier it is to have genetic defects (so stop having the myth of raising famous dogs and purebred dogs) ), Labrador Retriever is one of them, they have the genetic defect of skeletal dysplasia, as in the second half of the movie, Ke Lu suffers from skeletal dysplasia, walking more and more slowly and stop-and-go He stopped and even limped. Later, he fell and was seriously injured when he did not step on the stairs properly. Finally, he was released in the warm embrace of the owner.

Most purebred dogs have congenital genetic defects, such as Dalmatian congenital Deafness, PoodlePoodle epilepsy, Boxer with malignant tumor, du Penndogs have bleeding problems similar to hemophilia. There are about 22 kinds of dogs with congenital genetic defects related to vision:

Miniature long-haired dachshund, Norwegian elkhound, Irish setter, Miniature Schnauzer, Miniature poodle, Toy poodle, Chishapeake Chesapeake Bay retriever, Labrador retriever, American cocker spaniel, English cocker spaniel, English jumping spaniel springer spaniel, Siberian Husky, Sloughi, Briard, Old English mastiff, Bull Mastiff, Samoyed, Tibetan terrier, Cardigan Cardigan Welsh corgi, Australian cattle dog, Irish wolfhoundCorgi(Irish wolfhound), Japanese Akita(Japanese Akita).

The most common ophthalmic genetic defect in the above 22 kinds of dogs is commonly known as PRA or gPRA (Canine Generalized Progressive Retinal Atrophy), the full name of Canine Generalized Progressive Retinal Atrophy, referred to as Canine. Hereditary retinal degeneration is an important disease among dog eye diseases that causes retinal disease and blindness in dogs. PRA will occur in both eyes at the same time, but it will not feel pain. Fortunately, if the purebred dog raised by the owner happens to be listed in the above 22 species, there is no need to be too nervous, so if the DNA of the family blood does not carry the mutant gene of PRA, or it is several generations ago. If the relatives of the family do not have symptoms of PRA, this dog is not easy to get sick.

In addition, PRA does not necessarily only occur in the above purebred dogs. PRA may occur in most breeds dogs, as well as mixed-breed dogs. There are just many different types of retinal degenerative diseases in purebred dogs. In all breed studies, PRA is a recessive inheritance; PRA is dominant in the Old English mastiff and Bull mastiff, and is dominant in the Siberian Husky, The Samoyed is a sex-linked breed, so when a sex-linked dog is diagnosed with PRA, it is a male dog.