Shar Pei's impression on pet owners, short back, big head, small body, black nose, dark blue The tongue, and the most memorable thing is the deep wrinkles all over his body. Usually humans get wrinkles after they get old, so why do Shar Pei dogs have so many wrinkles? Today, the editor will give you some popular science for pet owners.

Researchers at the Autonomous University of Barcelona have found that all Shar Pei dogs have mucinosis, which is a genetic disorder. The significance of this research is that it can help Shar Pei breed better and help improve their health. Mucinosis in the Shar Pei is caused by the accumulation of hyaluronic acid (one of the main components of the intercellular spaces in tissue) in the skin structure. This cumulative effect results in very high concentrations of hyaluronic acid in their blood. After isolating fibroblasts from the skin of the Shar Pei for culture studies, the scientists confirmed that the massive synthesis of hyaluronic acid is due to abnormally increased activity (overexpression) of an enzyme called HAS2, which is responsible for the mammalian body One of three enzymes that synthesize acids.

Hyaluronic acid mainly exists in the space of various tissue cells, while the hyaluronic acid in the Shar Pei continuously accumulates in the skin tissue and blood vessels, eventually leading to the appearance of mucinosis. Scientists have shown that an enzyme called HAS2 is the perpetrator in a study of Shar Pei's skin fibroblast tissue.

What gene causes enzyme abnormalities, scientists are also in-depth research, the future research results will also make a huge contribution to human society. It can be seen that there are many treasures hidden in the Shar Pei. From now on, raise a Shar Pei and discover the unknown of life together with the editor!