Canine coronavirus infection (Canine coronavirus infection) is an acute gastrointestinal infectious disease with clinical features of diarrhea and vomiting. The disease can occur alone, and is often mixed with canine parvovirus, aggravating the course of the disease.

[Pathogen and Epidemiology]
1. Pathogen: Canine coronavirus (CCV), a member of the coronavirus genus. The virus is mainly present in the gastrointestinal tract of sick dogs and is excreted in the feces. The main route of transmission is through contaminated feed, drinking water, and mainly through the digestive tract.
2. Source of infection: Sick dogs and dogs with virus are the main sources of infection. The virus has strong resistance in the external environment. The virus in the feces can survive for 6 to 9 days, and the pollutants can remain infectious for several days in the water. Once the disease occurs, it is difficult to control its spread within a certain period of time.
3. Susceptible animals: Canines are susceptible, and some can infect pigs and cats. Dogs of all ages, breeds and genders are susceptible to CCV, with the highest incidence at 2-4 months of age.
4. Epidemiological characteristics: The incidence of CCV infection is very low, about 30%. distributed worldwide. Mostly in the cold winter, it spreads rapidly, and it often spreads to the whole litter within a few days.
[Symptoms]
The symptoms of the puppies were severe after infection, mainly manifested as gastroenteritis symptoms.
The vomiting persists for several days at the beginning of the illness, and the vomiting does not relieve or stop until the diarrhea occurs. Diarrheal stools are mushy, semi-mushy, or even watery, orange or green, and often contain mucus and blood.
Depressed spirit, like to lie down, anorexia, but low body temperature. Dehydration symptoms appear quickly in sick dogs, weight loss, especially if the puppies are not treated in time, they often die within 1 to 2 days. Adult dogs have mild symptoms.
【Diagnosis】
The clinical symptoms and epidemiology of this disease are similar to those of canine parvovirus and rotavirus infection, and often mixed infection, it is difficult to the difference. The feces of sick dogs should be collected for electron microscopy, virus isolation or fluorescent antibody examination, which is conducive to the diagnosis of the disease.
【Prognosis】
The mortality rate was higher in puppies than in morbidity and lower in adult dogs.
【Prevention and Treatment】
Serum was used for specific treatment. Supportive care maintains electrolyte and acid-base imbalances, while broad-spectrum antibiotics are used to prevent secondary infections. Focus on prevention.