Not only people can get uremia, but also dogs. Uremia is caused by kidney failure, and the accumulation of toxic substances in the body cannot be decomposed, causing huge harm to the body. Diseases like this It is often accompanied by some complications, so if the dog suffers from uremia, what symptoms will there be? How should the dog with uremia be treated?

Malthys

:

1. Because of the dog Various tissues and organs are damaged, so its clinical symptoms are also complex and diverse. Sick dog is extremely depressed, unconscious, sensory disturbance, lethargy: loss of appetite or abstinence, vomiting, gastrointestinal inflammation, mucosal ulcer, diarrhea, bloody stool, intestinal paralysis: increased blood pressure, cardiac insufficiency, pulmonary edema, congestion, breathing Shallow and frequent.

2. Due to metabolic disorder, the dog may be dehydrated, hyponatremia, calcium and hyperkalemia, phosphorus and magnesium hyperemia, significantly increased non-protein nitrogen content in blood, acidosis, hyperlipidemia. Impaired glucose tolerance, vitamin deficiency. Hyperphosphatemia further leads to abnormal calcium metabolism, vitamin D deficiency, and osteochondrosis and osteodystrophy in dogs, and can also be secondary to hyperparathyroidism. Since dogs are immunocompromised, they are prone to secondary infections.

3. Blood urea nitrogen is higher than 40 mg/100 ml, creatinine is higher than 4 mg/100 ml, blood sodium, calcium and carbonate are decreased. Serum potassium and phosphorus are increased.

4. Urine examination. The kidneys have the function of concentrating and diluting urine. In prerenal renal failure, the urine specific gravity is 1.025: renal renal failure is 1.008--1.012, indicating that the renal concentrating and diluting functions are reduced: post-renal renal failure, urine specific gravity varies. Oliguria and anuria are signs of critical illness (normally, 25 to 40 mg/kg of body weight per day in canine urine).

1. General treatment. Sodium bicarbonate is administered according to the degree of acidosis (detecting the binding capacity of plasma carbon dioxide), and a calcium-free infusion agent is selected to adjust hyperkalemia. Amino acids, high energy, vitamin preparations, etc. are supplemented in large quantities to improve hyperazotemia. For dogs with prerenal uremia, furosemide 2-4 mg/kg body weight, once every 8-12 hours, or diuric acid 1-2 mg/kg body weight, administered in 2 doses. When neurological symptoms appear, administer chlorpromazine 10-20 mg/kg body weight or phenobarbital 2-5 mg/kg body weight, orally 3 times a day.

2. Peritoneal dialysis. When blood urea nitrogen is 100 mg/100 mL, serum creatinine is 10 mg/100 mL, and serum potassium is 6 mmol/L, peritoneal dialysis can be applied. Dialysate is a calcium-free liquid. Intermittent peritoneal perfusion method is relatively simple. For dogs with severe water retention, hypertonic glucose perfusate can be used. If the symptoms are relieved and then relapse after repeated perfusion, it indicates that the kidneys have completely lost their function. poor prognosis.

3. Intermittent peritoneal perfusion method: the abdominal wall is sterilized by shearing, punctured with an ascites trocar, and a porous cannula is inserted. Pull out the cannula, indwelling cannula. After the perfusate is heated, 50-150 ml/kg is injected each time, and after 40 minutes of retention, the fluid is drained naturally and repeated 2-3 times. The perfusate is usually formulated with sodium lactate.

4. When the pulmonary edema is severe, the compound preparation of glucose and sodium lactate with high osmotic pressure should be mixed. Because the perfusate does not contain potassium chloride, for dogs with hypokalemia, 4 ml of potassium chloride (4 mmol/l) should be added per liter of perfusate.