Canine parvovirus is one of the three major infectious diseases of dogs. It is undoubtedly a nightmare for dogs, especially puppies, to be infected. It has the characteristics of high infectivity, high mortality, and great physical harm, so it is best for us to do preventive work for this disease, and try our best to prevent dogs from contracting this virus.

American Foxhound

Parvovirus is one of the most serious infectious diseases that endanger dogs today. more serious, and the mortality rate is high.

Parvovirus can be prevented by vaccination. In theory, the incidence of vaccinated dogs is extremely low, but for dogs under three months or not on time. For vaccinated dogs, the possibility of small occurrences is greatly increased. Below is a detailed description of the symptoms that dogs have.

The dog was initially depressed, anorexia, and occasionally had fever, soft stools or mild vomiting, and later developed frequent vomiting and severe diarrhea. At first, the stool is gray, yellow or milky white with jelly-like mucus, and then a foul-smelling soy sauce-like or tomato-juice-like bloody stool is excreted. The sick dog was rapidly dehydrated, emaciated, with sunken eye sockets, messy coat, inelastic skin, cold ears, nose, and limbs, high depression, shock, and death.

We will find that the initial symptoms of parvovirus are very similar to the symptoms of dog cold, so how do we distinguish the two diseases from the symptoms?

First of all, when a dog catches a cold, the dog is usually dizzy, loves to sleep, and can't keep up with toys and delicious food. Feeling warmer to the touch than before, red eyes, runny nose, quick breathing, etc. In fact, the symptoms of a cold and a fever are basically the same.

In addition to the symptoms similar to the cold mentioned above, parvovirus is mainly gastrointestinal symptoms, diarrhea and vomiting are the most obvious symptoms, and it will become more and more serious, vomiting and diarrhea with blood. Case. It is worth mentioning that parvovirus is very easy to distinguish in animal hospitals. There are relative test strips or blood tests, which can be diagnosed as soon as they are checked, so if you suspect that the dog is not a simple cold, go immediately. The hospital, check it out, is the most practical and safe way.

Canine parvovirus disease is an acute infectious disease of dogs caused by canine parvovirus infection. Its clinical manifestations include two types, namely enteritis type and myocarditis type. Enteritis type is more common and has 4 main features: (1) The body temperature rises at the beginning of the disease, reaching 40-41 °C; (2) Vomiting and then diarrhea, the stool is yellow or grayish yellow at first, and then turns tomato juice-like, with a fishy smell , especially unpleasant; ③ After vomiting and diarrhea, there are obvious symptoms of dehydration, weakness, weight loss, depression, sunken eyes, and reduced skin elasticity; ④ In the later stage, the anus relaxes, blood in the stool, falls into a coma, and the body temperature drops below 37℃ , and finally due to electrolyte imbalance complicated by acidosis and death. From the perspective of breeds, the disease mainly occurs in small dogs breeds, mostly foreign breeds, and rare in local breeds and large dogs; from the point of view of age of onset, The disease mostly occurs in puppies under the age of 5 months, and rarely occurs in adult dogs; from a seasonal point of view, it occurs more frequently from February to June, and is less common in other seasons.

There is no specific drug for the treatment of canine parvovirus enteritis, and comprehensive treatment measures should be taken clinically. The commonly used methods are: symptomatic therapy + supportive therapy + specific therapy + traditional Chinese medicine therapy.

1. Symptomatic therapy

The main features of canine parvovirus enteritis are vomiting, diarrhea, and blood in the stool. Symptomatic therapy should focus on these three keys. Antiemetic drugs such as Emerol, metoclopramide, VB6, atropine, and chlorpromazine can be used. In clinical practice, intramuscular injection of Amore should be the first choice, and atropine should be used if necessary, and metoclopramide should not be used in patients with gastrointestinal bleeding. Antidiarrheal can use tannin protein, Shimida. Because the sick dog vomits, it is not suitable for oral administration, and it is best to use deep enema. In order to prevent and treat intestinal bleeding, epinephrine, ampulic acid, amplimic acid, Anluoxue, Zhixuemin, VK3, VK1 can be used. If the effect of intramuscular injection is unsatisfactory, it can be combined with intramuscular injection or intravenous drip of Lihemostasis and sodium carboxylate.

2. Supportive therapy

The main effect of supportive therapy is to maintain cardiac function, regulate acid-base balance, and restore body condition as soon as possible. The most commonly used method is Cardiac rehydration. Infusion can be applied 0.9% sodium chloride solution, Ringer's solution, 5% sugar saline. When used in puppies under 4 months of age, the input amount of glucose solution should be increased. Infusion should be given at least once a day. For mild vomiting, oral rehydration salts can be used to drink: sodium chloride 3.5g, potassium chloride 1.5g, sodium bicarbonate 2.5g, glucose 20g, add water to 1000mL.

At the same time of infusion, attention should be paid to potassium, calcium and sodium bicarbonate.

Those who have fasted for more than 3 days should be supplemented with potassium, the dosage should be 0.1-0.2g per kilogram of body weight per day, and supplemented in 2-3 times; when potassium supplementation alone, the concentration should not exceed 3% ;If the concentration is too high, it can be diluted with 5%~10% glucose solution.

Calcium supplementation can often prevent hypocalcemic convulsions, and 10% calcium gluconate solution can be intravenously infused at a dose of 1 to 2 mg/kg.

Supplementing sodium bicarbonate solution can prevent acidosis. 5% sodium bicarbonate solution can be used, the dosage is 5mL/kg body weight, and it is diluted with 2 times the amount of 5% glucose or 10% glucose solution to make it. After becoming an isotonic solution, intravenous drip.

In order to protect the liver and strengthen the heart, ATP20～40mg, acetyl CoA100～200IU should be added to the intravenous solution, or 10% calcium gluconate solution should be intravenously injected alone.

3. Specific therapy

Canine parvovirus enteritis is a viral disease, and there is no specific drug for treatment. /kg), gentamicin (2-80,000 IU), dexamethasone (2-20 mg), gentamicin (40,000 IU), norfloxacin, etc. If the diagnosis is accurate and timely, in the early stage of the disease, the use of specific products such as hyperimmune serum, parvovirus monoclonal antibody, interferon, immunoglobulin, and Canine Life Source will be more effective.

4. Traditional Chinese Medicine

Recipe 1: Coptis 20g, Treats 30g, Scutellaria 50g, Muxiang 35g, Baishao 40g, Pueraria Root 20g, Burnet 30g, Banlangen 40g, turmeric 30g, gardenia 20g, Qianliguang 30g, big thistle 25g, small thistle 25g, licorice 15g. Decoction in water, 3 times a day, 1 dose on 2 days; when vomiting is severe, deep rectal administration can be selected.

Fang 2: 15g of turmeric, 20g of Pulsatilla, 10g of Coptis chinensis, 10g of Treats, 10g of Scutellaria, 10g of White Peony, 15g of Myrobalan, and 20g of Licorice. Decoction in water, 1 dose per day, 3 to 5 doses. Puppies are reduced.

Canine Parvovirus (CPV) for short is a disease with a relatively high fatality rate for dogs, and this virus is still prevalent all over the world. It is also one of the major infectious diseases that endanger dogs. To prevent canine parvovirus, vaccination and disinfection are very important.

CPV has strong resistance to the outside world and a long survival time, so it is extremely infectious. Once the disease occurs, the sick dog should be quickly isolated, and the kennel feeding tools, utensils, and transportation tools contaminated by the sick dog should be strictly disinfected. The disinfectant can be 2% NaOH, bleaching powder, potassium hypochlorite, etc. Repeated disinfection can use ultraviolet radiation. And stop for 2 weeks. Breeders should be strictly sterilized and flow restricted to avoid indirect infection.

Vaccine immunization is the fundamental measure for prevention. However, immune failure may occur, which is related to vaccine quality and immune interference. Mainly due to the improper selection of vaccine strains and the interference of maternal antibodies. Vaccines should be of reliable quality. The first vaccination time is generally considered to be around 10 weeks of age. However, considering that puppies are susceptible to puppies before 10 weeks of age, the puppy dual vaccine (this vaccine) can generally be injected at 6 weeks of age. It can break through the interference of maternal antibodies), inject the six-joint vaccine at 10 weeks of age, and then inject the six-joint vaccine every 3 weeks, 2-3 times in a row, and then immunize once a year.