Canine coronavirus disease is an acute intestinal infectious disease caused by canine coronavirus. Canine coronavirus can cause different degrees of gastroenteritis symptoms in dogs, characterized by frequent vomiting, diarrhea, depression, anorexia and other symptoms. The disease can occur all year round, and it occurs frequently in winter. Dogs are the main infectious agent. Dogs can be infected through the respiratory tract, digestive tract, feces and pollutants. Once the disease occurs, the litter petdog and the housemate pet dog are difficult to control and can cause infection. The disease is often co-infected with canine parvovirus, rotavirus, and other gastrointestinal diseases.

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Canine coronavirus (CCV) is an enveloped, single-stranded RNA virus. The virus is mainly oral infection, invading the villous epithelial cells, and then the villi are thick and short, which makes the dog's digestive enzymes and intestinal absorption function lose, eventually leading to diarrhea. Viremia and infection of other internal organs have not been reported in this disease. For dogs, dogs of different breeds, genders and ages can be infected, and puppies are most susceptible to infection due to their poor resistance, with a morbidity rate of almost 100% and a case fatality rate of 50%. Sick dogs and infected dogs are the main sources of infection. The virus is transmitted to healthy dogs and other susceptible animals through the respiratory tract and digestive tract through direct and indirect contact. The disease can occur all year round, but mostly in winter. Changes in climate, poor sanitation, high density of dog populations, and stressful factors such as weaning, transfer, and long-distance transportation may all induce the disease.

Canine coronavirus disease is caused by canine coronavirus, which can infect all breeds and dogs of all ages (especially puppies), causing dogs to produce The symptoms of gastroenteritis vary in severity, including frequent vomiting, diarrhea, depression, and anorexia, which can recur 14 to 21 days after the clinical symptoms disappear. It is a major infectious disease that endangers the dog industry at present. The route of infection is the digestive tract, mainly due to exposure to feces and pollutants excreted by sick dogs. The virus survives 6 to 9 days in feces, and contaminants can remain infectious for several days in water. Canine coronavirus can react with antiserum of feline transmissible peritonitis virus and porcine transmissible gastroenteritis virus, indicating that the three may be a group of viruses. The virus is sensitive to heat, UV light and general chemicals.

The incubation period is 1 to 8 days. The disease spreads rapidly and can spread to the whole group within a few days. Usually, the symptoms are drowsiness, weakness, and repeated vomiting at first, and then the stool is mushy, semi-mushy to watery, orange or green, containing mucus or blood, fever or no fever, leukopenia, rapid dehydration, and death. Mortality decreases with age. Some cases do not show clinical symptoms. Canine coronaviruses are often co-infected with parvoviruses, constituting a canine diarrhea pandemic.

According to the local epidemic situation, whether there is a coronavirus epidemic; preliminary judgment of clinical characteristics; colloidal gold test strips (usually small and coronal at the same time).

Use symptomatic therapy, such as antiemetic, antidiarrheal, rehydration, use antibiotics to prevent secondary infection, immediately fast and water, coronavirus is a gastrointestinal disease, must fast and water, if gastrointestinal There is food and water in it, the bacteria will always be there and diarrhea will be more frequent, and then take it to the regular veterinary station for infusion of anti-inflammatory and nutrient solutions, and then infusion of serum, usually a seven-day course of treatment can recover, the cure rate of coronary is 95% Left and right (what the doctor at the veterinary station said), vaccines have no preventive effect on canine coronavirus disease. The measures to reduce the incidence are to strengthen feeding management and strictly implement veterinary hygiene measures.

Intravenous fluids required due to inability to fast due to vomiting during illness. After the situation improves, let him slowly take the initiative to eat some digestible food. After the dog recovers from the disease, the intestinal damage still does not fully recover. It is best to give some intestinal prescription food to reduce the burden on the gastrointestinal tract, but the process of changing should be gradual instead of changing at one time; or supplement some intestinal probiotics and put Dog food is soft enough to eat.

Do not keep other animals in the house within six months, not only dogs, but also cats. Due to the homology between canine coronavirus and feline coronavirus, cross-infection may occur, leading to infectious enteritis or even FIP in cats. After half a month of illness, you can do an immunization to prevent other virus infections.