The diet of corn snakes includes small rodents, lizards, frogs, small birds, fish, and eggs, while the young eat mainly insects. Home corn snakes are best fed white mice and small lizards, but lizards are more difficult to find, and lizards are corn snakes' favorite food.

When the corn snake eats, it is best to put it in a quiet place to avoid being frightened. Spitting out the food will cause damage to the stomach of the corn snake, and even lead to serious Corn snakes are dying.