The North Pole Viper has been included in the Red List of Chinese Biodiversity - Vertebrate Volume - Endangered (EN). It has been listed in the List of Beneficial or Important Economic and Scientific Research Terrestrial Wild Animals under National Protection issued by the State Forestry Administration of China on August 1, 2000. It has been included in the fourth category of protected animals in the Interim Regulations on the Protection and Management of Wild Animals and Plants in Jilin Province promulgated and implemented by the Standing Committee of the Jilin Provincial People's Congress on March 3, 1985 .

In some countries, the northern viper is a protected animal, such as the United Kingdom. But its venom is a detriment to conservation efforts, and the species is hunted out of fear of the northern viper. At the same time, habitat destruction due to agricultural development, deforestation and shrub erosion is also threatening the North Pole Viper .