The big-eyed oblique-scale snake will not take the initiative to attack people. Under normal circumstances, the big-eyed oblique-scale snake will leave as soon as possible when it encounters a human being. It will only attack and defend itself when it feels threatened. It resembles a cobra and is often mistaken for poisonous.

The big-eyed oblique-scale snake lives in the plateau mountains, On mountain streams, roadsides, vegetable gardens, and stone piles, they mainly feed on predatory frogs. When the big-eyed oblique-scale snake is frightened, the front part of the body is raised, whistling, and sometimes it is often coiled on the small stone.