When the red-faced mud turtle has rotten skin, if the symptoms are mild, it can be dry-raised for a period of time without medication to keep the body of the red-faced mud turtle dry.

If the symptoms are severe, drug treatment is required. It can be treated by applying drugs such as povidone-iodine or erythromycin, or it can be combined with drugs such as amoxicillin, but the course of treatment is relatively long and requires patience and careful treatment.