Hainan rabbits will become sexually mature after about a year. After sexual maturity, Hainan rabbits begin to mate at the end of spring. They produce more than 3 litters each year, with 2-10 litters per litter, with an average of 3-5 litters.

The reason why Hainan rabbits start mating in late spring is to keep the young rabbits in the Born during the warmest season of the year. Hainan rabbits breed several times a year, with a gestation period of about 30 days.