Desert cottontail rabbits are very easy to feed. They are mainly fed on hay. They do not need to feed too much food with high water content. Drinking too much water will cause stomach discomfort in desert cottontail rabbits. Desert cottontail rabbits are very vigilant and not timid, especially when eating food, they will run away quickly when they are frightened, so be careful when feeding them, so as to avoid desert cottontail rabbits running and bumping their heads.

The desert cottontail rabbit is an interesting rabbit with great adaptability , the vitality is also very tenacious. There are no sweat glands, so there is no sweating, the ears can dissipate heat, and the demand for water is less than that of other animals. It only needs to rely on the dew on the grass, so it is rare to see desert cottontail rabbits drinking water.

Desert cottontail rabbits mainly live in arid areas, where the temperature is usually higher. Desert cottontail rabbits are most active at dawn and dusk, and rest in their burrows during the hottest hours. On hot summer days, they conserve moisture and energy by avoiding activity.