American tawny rabbits come into heat at 6 months and then breed. The gestation period of the American tawny rabbit is generally one month. The birth time of American tawny rabbits is usually in the middle of the night or early morning, and the labor will be completed in about ten to thirty minutes.

The newborn American tawny rabbit has no fur, ears close to the back of the head, eyes closed, and small teeth. Baby American tawny rabbits will start to grow hair in a week, eyes will open in about a week, ears will open in about 12 days, and by 16 to 18 days they will walk around and can eat solid food , about six to eight weeks will be completely weaned.