White-tailed jackrabbits are widely distributed in Canada and the United States and other places, and their numbers have declined. They have been included in the International Union for Conservation of Nature (IUCN) ver 3.1: 2008 Mammalia Lagoidae Red List -- Low Risk (LC), generally not traded, so the price is unknown.

The size of the white-tailed jackrabbit is larger than the average rabbit It is much larger, so it is often preyed by some carnivores, such as wolves, eagles, mountain dogs and foxes. But its scarcity is more due to environmental changes and human hunting, and it needs to be further protected.