The Bichon Frise reaches sexual maturity in 6 to 8 months and physical maturity in 12 months, and can mate and breed when it reaches physical maturity. Bichon Frise bears estrus twice a year in spring and autumn, with a gestation period of 58 to 65 days, and 4 to 6 per litter.

When the female Bichon Frise gives birth , requires careful care. Because the female Bichon Frise usually does not eat after giving birth, you can feed some glucose water first, and add some eggs and milk after 5-6 hours, until the feeding officially starts after 24 hours.