The U.S. Food and Drug Administration (FDA) has approved Zenalpha (Medetomidine and Vatinoxan, a combination of medetomidine and vetenoxan hydrochloride injection) as a sedative and analgesic in dogs to help dogs during examinations or Calmness and pain relief during certain medical procedures.

Medetomidine, a sedative with pain-relieving properties, is known to reduce the heart rate in animals and increase the chance of arrhythmias (arrhythmias), while Vatinoxan can increase the heart rate in dogs It fluctuates within the normal range, thereby reducing the negative effects of medetomidine on cardiovascular, and can also effectively improve cardiovascular function and improve the safety of medetomidine.